Why Is AMPk Activation Important?
AMPK is an enzyme essential for maintaining energy balance. It consists of 3 proteins (called sub-units) that together create a functional enzyme. AMPK is expressed in various tissues, including the brain, liver, skeletal muscle, and fat cells. The net effects of AMPK activation include ketogenesis, stimulation of hepatic fatty acid oxidation, inhibition of cholesterol synthesis, triglyceride synthesis, and lipogenesis, and the stimulation of glucose uptake and skeletal muscle fatty acid oxidation.